INVOS^® System
by Specialty

Key Study Findings - Patient Information

Here's a look at some of our most compelling and significant studies demonstrating that using the INVOS^® System on adults, children, infants and neonates can make a positive difference.

Study Shows Improved Outcomes

A clinical study of 200 coronary artery bypass (CAB) patients¹ showed that patients who received active INVOS^® System monitoring experienced a decrease in the combined incidence of stroke, ventilation time, sternal infection, kidney failure, re-operation and death within 30 days.
In medicine, this group of cumulative adverse conditions is known as Major Organ Morbidity or Mortality (MOMM)².
Only 3% of the patients who received active INVOS^® System monitoring experienced one or more of the complications that constitute MOMM - instead of 11% in the unmonitored group. According to the Society of Thoracic Surgeons (STS), MOMM is at 13.4%!
INVOS^® System-monitored patients also had a shorter ICU stay and fewer, prolonged brain-oxygen deficits.

Footnotes:
1. Murkin JM, et al. Anesth Analg. 2007 Jan;104(1):51-8.
2. Shroyer AL, et al. Ann Thorac Surg. 2003;Jun:75(6):1856-64.

Stroke and Prolonged Ventilation Were Reduced

A large study on over 2,000 cardiac surgery patients found that INVOS^® System monitoring helped reduce the stroke rate, ventilation time and hospital length of stay.
These statistically-significant results were achieved despite the fact that the INVOS^® System monitored group contained much sicker patients.
Just think: these benefits were possible because of the aid of a simple, pain-free monitor!

Footnotes:
1. Goldman et al. Heart Surgery Forum 2004;7(5):E376-81.
2. Goldman et al. Presented at Outcomes 2005, May 19-22, Key West.

Study Shows Shorter Hospital Stay

This clinical study on relatively healthy, elderly patients undergoing abdominal surgery showed that those patients with a brain oxygenation problem who received interventions by their care team left the hospital a whole lot sooner than those who did not receive interventions: 10 days versus 24 days. That's a 58% shorter hospital stay!
Plus, those who did not receive interventions to correct their oxygen imbalance also scored lower on the post-op Mini-Mental State Examination (MMSE), a reflection of brain function.
This study showed that one in five patients - 20% - experienced a cerebral oxygenation problem detected by the INVOS^® System.
Pulse oximetry, a standard vital sign, did not indicate these critical oxygenation problems.
Corrective interventions made to the patients were as simple as adjusting anesthesia dosage.

Footnote:
Casati A, et al. Anesth Analg. 2005 Sep;101(3):740-7.

INVOS^® System is Safe, Reliable and Pain-free

Sick children and babies have to undergo enough invasive tests. With the INVOS^® System, there are no needle pokes. Sensors simply adhere to the skin like a BandAid^®.

This clinical study on pediatric patients showed that noninvasive INVOS^® System data could be used to predict changes in SvO₂ - an invasive test performed with a needle to help determine if a patient's whole-body oxygen balance is at healthy levels.
The investigators state that INVOS^® System technology "addresses a number of the limitations of SvO₂ monitoring." For instance, the INVOS^® System is noninvasive and can identify the oxygenation levels in up to four distinct organ beds.
Safe, reliable and pain-free monitoring makes care teams and patients breathe easier.

Footnote:
Hoffman GM et al. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2005:12-21.

We're Keeping Infants Safer After Surgery

This clinical study showed that brain injury can occur or worsen in the period shortly after an infant's surgery.
The ability to detect and correct low brain oxygen levels is crucial to improving safety.
Using the INVOS^® System to detect oxygenation problems may reduce subsequent neurological challenges.
This study found that brain oxygen monitoring after surgery is as important as monitoring during surgery.