Infant/Neonatal


This bibliography contains a link to the abstract or document when available. These links may take you to a web site such as PubMed, a service of the US National Library of Medicine. Some of these links may require a search. The third party website links listed are not affiliated with Somanetics, and Somanetics does not endorse or warrant the content, services or products of such third party websites.

* = Abstract

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Congenital Heart Disease


Andropoulos DB, Diaz LK, East DL, McKenzie ED, Fraser CD Jr. Intraoperative cerebral oxyhemoglobin saturation in neonates undergoing cardiac surgery with cardiopulmonary bypass. Anesthesiology 2005;103:A1376.
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Andropoulos DB, East DL, Eble BK, Stapleton GE, Chang AC. Perioperative intestinal regional oxygen saturation index (rSO2i) in neonates undergoing cardiac surgery. Anesthesiology 2005;103:A1331.
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Andropoulos DB, East DL, Eble BK, Stapleton GE, Chang AC. Preoperative cerebral oxyhemoglobin saturation in neonates undergoing cardiac surgery with cardiopulmonary bypass. Anesthesiology 2005;103:A1341.
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Andropoulos DB, East DL, Stapleton GE, Eble BK, Chang AC. Postoperative cerebral oxyhemoglobin saturation in neonates undergoing cardiac surgery with cardiopulmonary bypass. Anesthesiology 2005;103:A1340.
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Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2005 Dec;130(6):1523-30.
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Dibardino DJ, Allison AE, Vaughn WK, McKenzie ED, Fraser CD Jr. Current expectations for newborns undergoing the arterial switch operation. Ann Surg. 2004 May;239(5):588-96; discussion 596-8.
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Diaz LK, McKenzie ED, Miller-Hance WC, Andropoulos DB, East DL. The effect of mechanical limitation of pulmonary blood flow on systemic and cerebral oxygen saturations in infants with single ventricle physiology. Anesthesiology 2004;101:A1444.
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Fenton KN, Freeman K, Glogowski K, Fogg S, Duncan KF. The significance of baseline cerebral oxygen saturation in children undergoing congenital heart surgery. Am J Surg. 2005 Aug;190(2):260-263.
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Fenton KN, Lessman K, Glogowski K, Fogg S, Duncan KF. Cerebral oxygen saturation does not normalize until after stage 2 single ventricle palliation. Ann Thorac Surg. 2007 Apr;83(4):1431-6.
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Hofer A, Haizinger B, Geiselseder G, Mair R, Rehak P, Gombotz H. Monitoring of selective antegrade cerebral perfusion using near infrared spectroscopy in neonatal aortic arch surgery. Eur J Anaesthesiol. 2005 Apr;22(4):293-8.
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Hoffman GM, Ghanayem NS, Mussatto KA, Berens RJ, Tweddell JS. Postoperative two-site NIRS predicts complications and mortality after Stage 1 Palliation of HLHS. Anesthesiology 2007; 107: A234.
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Hoffman GM, Stuth EA, Berens RJ, Robertson FA, Troshynski TJ. Two-site near-infrared transcutaneous oximetry as a non-invasive indicator of mixed venous oxygen saturation in cardiac neonates. Anesthesiology 2003;99:A1393.
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Hoffman GM, Stuth EA, Berens RJ, Staudt SA, Strong TC. Two-site NIRS reveals impaired systemic oxygen delivery during anesthesia induction in critically ill neonates with hypoplastic. Anesthesiology 2005;103:A1328.
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Ing RJ, Lawson DS, Jaggers J, Schulman S, Shearer IR, Kern FH. Detection of unintentional partial superior vena cava occlusion during a bidirectional cavopulmonary anastomosis. J Cardiothorac Vasc Anesth. 2004 Aug;18(4):472-4. [Case Report]
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Johnson BA, Hoffman GM, Tweddell JS, Cava JR, Basir M, Mitchell ME, Scanlon MC, Mussatto KA, Ghanayem NS. Near-infrared spectroscopy in neonates before palliation of hypoplastic left heart syndrome. Ann Thorac Surg. 2009 Feb;87(2):571-7; discussion 577-9.
Johnson B, Tweddell JS, Cava JR, Hoffman GM, Basire M, Mussatto KA, Scanlon MC, Mitchell ME, Ghanayem NS. Clinical utility of near-infrared spectroscopy in neonates prior to stage 1 palliation of hypoplastic left heart syndrome. Presented at Society of Thoracic Surgeons, Fort Lauderdale, Florida, January 29, 2008.

Kirshbom PM, Forbess JM, Kogon BE, Simsic JM, Kim DW, Raviele AA, Kanter KR, Vincent RN. Cerebral near infrared spectroscopy is a reliable marker of systemic perfusion in awake single ventricle children. Pediatr Cardiol. 2007 Jan-Feb;28(1):42-5. Epub 2007 Jan 2.
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Kussman BD, Gauvreau K, DiNardo JA, Newburger JW, Mackie AS, Booth KL, del Nido PJ, Roth SJ, Laussen PC. Cerebral perfusion and oxygenation after the Norwood procedure: comparison of right ventricle-pulmonary artery conduit with modified Blalock-Taussig shunt. J Thorac Cardiovasc Surg. 2007 Mar;133(3):648-55.
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Lemmers PM, Toet MC, van Bel F. Impact of patent ductus arteriosus and subsequent therapy with indomethacin on cerebral oxygenation in preterm infants. Pediatrics. 2008 Jan;121(1):142-7.
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Rice-Townsend S, Ramamoorthy C, Dutta S. Thoracoscopic repair of a type D esophageal atresia in a newborn with complex congenital heart disease. J Pediatr Surg. 2007 Sep;42(9):1616-9. [Case Report]
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Rossi M, Tirotta CF, Lagueruela RG, Madril D. Diminished Blalock-Taussig shunt flow detected by cerebral oximetry. Paediatr Anaesth. 2007 Jan;17(1):72-4. [Case Report]
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Simsic JM. Cerebral oximetry via near-infrared spectroscopy: A non-invasive indicator of mixed venous oxygen saturation in neonates before and after cardiac surgery. INVOS® Cerebral Oximeter Clinical White Paper Series 2005;412(1):1-4.
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Toet MC, Flinterman A, Laar I, Vries JW, Bennink GB, Uiterwaal CS, Bel F. Cerebral oxygen saturation and electrical brain activity before, during, and up to 36 hours after arterial switch procedure in neonates without pre-existing brain damage: its relationship to neurodevelopmental outcome. Exp Brain Res. 2005 Sep;165(3):343-50. Epub 2005 Jun 7.
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Tosone SR, Miller BE, Guzzetta NA, Kanter KR, Forbess JM. Cerebral oxygen saturation monitoring is a useful adjunct in assessing adequacy of systemic perfusion in single ventricle physiology after neonatal cardiac surgery. Anesthesiology 2003;99:A1392.
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Zabala L, Ullah S, Schmitz ML, Watkins WB. Cerebral and somatic near infrared spectroscopy (NIRS) during Kasai portoenterostomy in a neonate following first stage palliation for hypoplastic left heart syndrome (HLHS). Presented at Pediatric Anesthesiology 2006, February 16-19, 2006, Fort Myers, Florida.

Respiratory Distress/Mechanical Ventilation


Campos Lopez CJ, East DL, Andropoulos DB, Stayer SA, Miller-Hance WC. The effect of FiO2 on hemodynamics, mixed venous and cerebral oxygen saturation in infants with large intracardiac shunts. Anesthesiology 2004;101:1511.
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Hoffman GM, Ghanayem NS, Musa N, Mussatto KA, Berens RJ. Differential effects of carbon dioxide tension on cerebral and somatic oxygenation assessed by near infrared spectroscopy in postoperative neonates. Anesthesiology 2005;103:A1374.
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Lemmers PM, Toet M, van Schelven LJ, van Bel F. Cerebral oxygenation and cerebral oxygen extraction in the preterm infant: the impact of respiratory distress syndrome. Exp Brain Res. 2006 Aug;173(3):458-67. Epub 2006 Feb 28.
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Mott AR, Alomrani A, Tortoriello TA, Perles Z, East DL, Stayer SA. Changes in cerebral saturation profile in response to mechanical ventilation alterations in infants with bidirectional superior cavopulmonary connection. Pediatr Crit Care Med. 2006 Jul;7(4):346-350.
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ECMO/CPB Techniques


Ejike JC, Schenkman KA, Seidel K, Ramamoorthy C, Roberts JS. Cerebral oxygenation in neonatal and pediatric patients during venoarterial extracorporeal life support. Pediatr Crit Care Med. 2006 Mar;7(2):154-8.
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Gardner AB, Eghtesady P. Infant arch reconstruction during total system perfusion. J Thorac Cardiovasc Surg. 2007 Apr;133(4):1096-8.[Case Report]
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Rodriguez RA, Ruel M, Broecker L, Cornel G. High flow rates during modified ultrafiltration decrease cerebral blood flow velocity and venous oxygen saturation in infants. Ann Thorac Surg. 2005 Jul;80(1):22-8.
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Hypoxia/Birth Asphyxia/Seizures


Alfonso I, Vasconcellos E, Shuhaiber HH, Yaylali I, Papazian O. Bilateral decreased oxygenation during focal status epilepticus in a neonate with hemimegalencephaly. J Child Neurol. 2004 May;19(5):394-6. [Case Report]
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Diaz GA, Cesaron E, Alfonso I, Dunoyer C, Yaylali I. Near infrared spectroscopy in the management of status epilepticus in a young infant. Eur J Paediatr Neurol. 2006;10(1):19-21. Epub 2006 Mar 10. [Case Report]
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Petrova A, Mehta R. Near-infrared spectroscopy in the detection of regional tissue oxygenation during hypoxic events in preterm infants undergoing critical care. Pediatr Crit Care Med. 2006 Sep;7(5):449-54.
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Shuhaiber H, Bolton S, Alfonso I, Dunoyer C, Yaylali I. Cerebral regional oxygen fluctuations and decline during clinically silent focal electroencephalographic seizures in a neonate. J Child Neurol. 2004 Jul;19(7):539-40. [Case Report]
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Tobias JD. Cerebral oximetry monitoring provides early warning of hypercyanotic spells in an infant with tetralogy of Fallot. J Intensive Care Med. 2007 Mar-Apr;22(2):118-20. [Case Report]
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Toet MC, Lemmers PM, van Schelven LJ, van Bel F. Cerebral oxygenation and electrical activity after birth asphyxia: their relation to outcome. Pediatrics. 2006 Feb;117(2):333-9.
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Mesenteric Monitoring


Kaufman J, Almodovar MC, Zuk J, Friesen RH. Correlation of abdominal site near-infrared spectroscopy with gastric tonometry in infants following surgery for congenital heart disease. Pediatric Critical Care Medicine 2008;9(1):62-68. Continuing Medical Education Article
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Meier SD, Eble BK, Stapleton GE, Morales DL, Chang AC, Andropoulos DB. Mesenteric oxyhemoglobin desaturation improves with patent ductus arteriosus ligation. J Perinatol. 2006 Sep;26(9):562-4.
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Stapleton GE, Eble BK, Dickerson HA, Andropoulos DB, Chang AC. Mesenteric oxygen desaturation in an infant with congenital heart disease and necrotizing enterocolitis. Tex Heart Inst J. 2007;34(4):442-4.
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Stapleton GE, Eble BK, East DK. Mott AR, Dickerson HA, Price JF, McKenzie ED, Fraser CD, Andropoulos DB, Chang AC. Mesenteric regional oximetry in neonates undergoing cardiac surgery: A new assessment methodology of systemic oxygen delivery using nearinfrared spectroscopy. J Am Coll Cardiol 2006;47(4)242A:989-110.
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Need for Monitoring


Li J, Zhang G, Holtby H, Guerguerian AM, Cai S, Humpl T, Caldarone CA, Redington AN, Van Arsdell GS. The influence of systemic hemodynamics and oxygen transport on cerebral oxygen saturation in neonates after the Norwood procedure. J Thorac Cardiovasc Surg. 2008 Jan;135(1):83-90, 90.e1-2.
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Verhagen E A, ter Horst H J, Keating P, Bos A F. The course of cerebral oxygen saturation and oxygen extraction during the first two weeks of life in pre term infants. Acta Paediatrica 96 (s456), 1-245.
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